Gönül Aslan · 2024 · Journal of clinical practice and research · added 2026-04-24
Tuberculosis (TB) poses significant health challenges globally, contributing significantly to illness and mortality. Approximately one-fourth of the world's population is believed to carry the tubercu Show more
Tuberculosis (TB) poses significant health challenges globally, contributing significantly to illness and mortality. Approximately one-fourth of the world's population is believed to carry the tuberculosis bacterium, with a 5-10% lifetime risk of developing active TB disease. Timely identification of TB and rapid detection of drug resistance are crucial in mitigating its global impact. Clinical, radiological, bacteriological, and molecular methods are used to screen and diagnose TB. Microscopy, culture, and immunological methods are commonly employed. Although microscopy has been used for approximately a century, it has limitations, necessitating its use and evaluation alongside other diagnostic techniques for a complete and accurate diagnosis. Bacterial culture in solid and liquid media is still the gold standard recommended by the World Health Organization (WHO) for the diagnosis of TB, as it enables the isolation of Show less