👤 Morgane Mannes

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Articles

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Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design.

Luis E Gimenez, Charlotte Martin, Jing Yu +15 more · 2024 · Journal of medicinal chemistry · ACS Publications · added 2026-04-24

Luis E Gimenez, Charlotte Martin, Jing Yu, Charlie Hollanders, Ciria C Hernandez, Yiran Wu, Deqiang Yao, Gye Won Han, Naima S Dahir, Lijie Wu, Olivier Van der Poorten, Arthur Lamouroux, Morgane Mannes, Suwen Zhao, Dirk Tourwé, Raymond C Stevens, Roger D Cone, Steven Ballet Show less

Melanocortin 4 receptor (MC4-R) antagonists are actively sought for treating cancer cachexia. We determined the structures of complexes with

no PDF DOI: 10.1021/acs.jmedchem.3c01822

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