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The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling.

Athiththan Yogeswaran, Christian Troidl, James W McNamara +7 more · 2021 · Cells · MDPI · added 2026-04-24

Athiththan Yogeswaran, Christian Troidl, James W McNamara, Jochen Wilhelm, Theresa Truschel, Laila Widmann, Muhammad Aslam, Christian W Hamm, Sakthivel Sadayappan, Christoph Lipps Show less

Myocardial injury is associated with inflammation and fibrosis. Cardiac myosin-binding protein-C (cMyBP-C) is cleaved by µ-calpain upon myocardial injury, releasing C0-C1f, an

no PDF DOI: 10.3390/cells10061326

MYBPC3

👤 Theresa Truschel

The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling.