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Vali Musazadeh, Rogheye Yaraee Rostami, Amir Hossein Moridpour +4 more ยท 2024 ยท BMC cardiovascular disorders ยท BioMed Central ยท added 2026-04-24
Glucomannan has been studied for various health benefits, but its effects on lipid profile in adults are not well understood. This meta-analysis aims to evaluate the impact of glucomannan supplementat Show more
Glucomannan has been studied for various health benefits, but its effects on lipid profile in adults are not well understood. This meta-analysis aims to evaluate the impact of glucomannan supplementation on serum/plasma levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), Apo B1, Apo A1, APO-B/ A1 ratio, and LDL-C/ HDL-C in adults. A comprehensive search was conducted across Scopus, PubMed, Embase, and Web of Science from inception to June 2024 to identify randomized controlled trials (RCTs) assessing glucomannan supplementation on lipid profile in adults. Data were extracted and analyzed using random effects model to determine the standardized mean differences (SMDs) and 95% confidence intervals (CIs) for each biomarker. Glucomannan supplementation significantly decreased TC (SMD: -3.299; 95% CI: -4.955, -1.664, Pโ€‰<โ€‰0.001; I Glucomannan supplementation has a beneficial effect on the level of TC and LDL-C. Show less
๐Ÿ“„ PDF DOI: 10.1186/s12872-024-04223-0
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