BackgroundAlzheimer's disease (AD) is a progressive neurodegenerative characterized by amyloid-β (Aβ) peptide aggregation and tangles. Protein translation deregulation and viral exposures, including S Show more
BackgroundAlzheimer's disease (AD) is a progressive neurodegenerative characterized by amyloid-β (Aβ) peptide aggregation and tangles. Protein translation deregulation and viral exposures, including SARS-CoV-2, have been implicated in increased AD risk. Genes such as YIF1A, PABPC4, and MRPS27, which are involved in mRNA translation and protein folding have been linked to neurodegeneration and host responses to SARS-CoV-2.ObjectiveThis study investigates the association of three genetic variants, rs7945723G>A Show less