Human genetic variants near the FADS (fatty acid desaturase) gene cluster ( Here, we specifically investigated the physiological role of the ฮ-5 desaturase FADS1 in regulating diet-induced cardiometab Show more
Human genetic variants near the FADS (fatty acid desaturase) gene cluster ( Here, we specifically investigated the physiological role of the ฮ-5 desaturase FADS1 in regulating diet-induced cardiometabolic phenotypes by treating hyperlipidemic LDLR (low-density lipoprotein receptor)-null mice with antisense oligonucleotides targeting the selective knockdown of These results position Show less