👤 Ruth R Wexler
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Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor.
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Heather J Finlay
,
Ji Jiang
,
Richard Rampulla
+18 more
· 2019 · ACS medicinal chemistry letters · ACS Publications
· added 2026-04-24
Heather J Finlay
,
Ji Jiang
,
Richard Rampulla
,
Mark E Salvati
,
Jennifer X Qiao
,
Tammy C Wang
,
R Michael Lawrence
,
Lalgudi S Harikrishnan
,
Muthoni G Kamau
,
David S Taylor
,
Alice Ye A Chen
,
Xiaohong Yin
,
Christine S Huang
,
Ming Chang
,
Xue-Qing Chen
,
Paul G Sleph
,
Carrie Xu
,
Julia Li
,
Paul Levesque
,
Leonard P Adam
,
Ruth R Wexler
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Lead optimization of the diphenylpyridylethanamine (DPPE) and triphenylethanamine (TPE) series of CETP inhibitors to improve their pharmaceutical profile is described. Polar groups at the
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DOI:
10.1021/acsmedchemlett.9b00086
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CETP
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