👤 Ariel H Wein

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2
Articles
2
Name variants
Also published as: Tanita Wein
articles

CARD domains mediate anti-phage defence in bacterial gasdermin systems.

Tanita Wein, Adi Millman, Katharina Lange +10 more · 2025 · Nature · Nature · added 2026-04-24
Caspase recruitment domains (CARDs) and pyrin domains are important facilitators of inflammasome activity and pyroptosis
📄 PDF DOI: 10.1038/s41586-024-08498-3
DYM

Determination of the melanocortin-4 receptor structure identifies Ca

Jing Yu, Luis E Gimenez, Ciria C Hernandez +16 more · 2020 · Science (New York, N.Y.) · Science · added 2026-04-24
The melanocortin-4 receptor (MC4R) is involved in energy homeostasis and is an important drug target for syndromic obesity. We report the structure of the antagonist SHU9119-bound human MC4R at 2.8-an Show more
The melanocortin-4 receptor (MC4R) is involved in energy homeostasis and is an important drug target for syndromic obesity. We report the structure of the antagonist SHU9119-bound human MC4R at 2.8-angstrom resolution. Ca Show less
📄 PDF DOI: 10.1126/science.aaz8995
MC4R