👤 Rebecca A Yaworski

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The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation.

Meenakshi Sundaram, Kaitlin R Curtis, Mohsen Amir Alipour +8 more · 2017 · Journal of lipid research · added 2026-04-24
Recent cell culture and animal studies have suggested that expression of human apo C-III in the liver has a profound impact on the triacylglycerol (TAG)-rich VLDL
no PDF DOI: 10.1194/jlr.M077313
APOC3