The Cognitive, genetic and demographic data from 192 healthy middle-aged adults (50-63 years) from the PEARL-Neuro Database were analyzed using agglomerative hierarchical clustering. Neuropsychologica Show more
The Cognitive, genetic and demographic data from 192 healthy middle-aged adults (50-63 years) from the PEARL-Neuro Database were analyzed using agglomerative hierarchical clustering. Neuropsychological tests included the California Verbal Learning Test, Raven's Progressive Matrices, and the Edinburgh Handedness Inventory. Subsequent analyses used linear regression models to assess the effects of Two cognitive subgroups (better vs. worse performance) were identified for both females (n = 60/43) and males (n = 38/51). In women with lower cognitive performance, the presence of the This study revealed significant sex differences in gene-cognition interactions. In females with lower cognitive performance, the genotype Show less