Research focused on adult eating styles would benefit from investigating whether latent profiles of appetitive and emotion-related impulsivity traits differ in eating disorder (ED) and general psychop Show more
Research focused on adult eating styles would benefit from investigating whether latent profiles of appetitive and emotion-related impulsivity traits differ in eating disorder (ED) and general psychopathology. This study identified and validated latent eating profiles based on appetitive and emotion-related impulsivity traits. We conducted a cross-sectional study in a non-clinical sample of 232 adults who completed an online battery of questionnaires assessing appetitive traits, emotion-related impulsivity, ED symptomatology, anxiety, depression, stress, and other clinical and background characteristics. We fitted latent profile analysis (LPA) models with 2-8 classes on the dataset without multivariate outliers (N = 223). After retaining the best profile solution, we compared latent classes using ANCOVAs and Tukey post-hoc tests, controlling for age. The best-fitting model revealed four distinct profiles: Resilient Eaters (23.30%), with the lowest food responsiveness and emotion-related impulsivity; Moderate Eaters (46.27%), showing higher food avoidance and behavioral emotion-related impulsivity; Hedonic Eaters (14.03%), characterized by the highest enjoyment of food and lower emotion-related impulsivity; and Impulsive Eaters (16.40%), with the highest food responsiveness and emotion-related impulsivity. Resilient Eaters exhibited the most adaptive profile, with higher general and ED-specific flexibility and lower general ED psychopathology, depression, anxiety, and stress, compared to Moderate and Impulsive Eaters. Moderate and Hedonic Eaters showed intermediate levels of ED symptomatology and psychological distress, whereas Impulsive Eaters displayed the most maladaptive profile. Classifying eating profiles based on appetitive and impulsive traits has the potential to advance screening for complex forms of ED psychopathology. Show less
SARS-CoV-2 infection is a significant health concern that needs to be addressed not only during the initial phase of infection but also after hospitalization. This is the consequence of the various pa Show more
SARS-CoV-2 infection is a significant health concern that needs to be addressed not only during the initial phase of infection but also after hospitalization. This is the consequence of the various pathologies associated with long COVID-19, which are still being studied and researched. Lung fibrosis is an important complication after COVID-19, found in up to 71% of patients after discharge. Our research is based on scientific articles indexed in PubMed; in the selection process, we used the following keywords: "lung fibrosis", "fibrosis mediators", "fibrosis predictors", "COVID-19", "SARS-CoV-2 infection", and "long COVID-19". In this narrative review, we aimed to discuss the current understanding of the mechanisms of initiation and progression of post-COVID-19 lung fibrosis (PC-19-LF) and the risk factors for its occurrence. The pathogenesis of pulmonary fibrosis involves various mediators such as TGF-β, legumain, osteopontin, IL-4, IL-6, IL-13, IL-17, TNF-α, Gal-1, Gal-3, PDGF, and FGFR-1. The key cellular effectors involved in COVID-19 lung fibrosis are macrophages, epithelial alveolar cells, neutrophils, and fibroblasts. The main fibrosis pathways in SARS-CoV-2 infection include hypoxemia-induced fibrosis, macrophage-induced fibrosis, and viral-fibroblast interaction-induced fibrosis. Show less