Acute kidney injury (AKI) represents a critical complication in patients with acute coronary syndrome (ACS), particularly in patients undergoing percutaneous coronary intervention (PCI). Current tests Show more
Acute kidney injury (AKI) represents a critical complication in patients with acute coronary syndrome (ACS), particularly in patients undergoing percutaneous coronary intervention (PCI). Current tests for detecting early AKI, such as creatinine and cystatin C, have modest sensitivity. This study explores the role of bioinformatics in creating an implementable predictive key gene in cardiorenal pathogenesis and evaluates the diagnostic potential of This is a single-center prospective observational cohort study that enrolled 167 participants: healthy controls ( The online version contains supplementary material available at 10.1186/s12882-026-04926-w. Show less