To investigate if epigenome of sperm cells could be dynamically affected by nutrition. We assessed 40 healthy volunteers with different dietary habits and collected their demographic characteristics, Show more
To investigate if epigenome of sperm cells could be dynamically affected by nutrition. We assessed 40 healthy volunteers with different dietary habits and collected their demographic characteristics, as well as clinical and anthropometric parameters. We compared methylation profiles in sperm quantified by bisulfite pyrosequencing, at promoter-associated CpG sites of genes involved in metabolism including fat mass and obesity-associated ( Higher DNA methylation levels were detected in the sperm of vegan at Although limited by the small number of investigated cases, our data provide insight into the role of diet on sperm DNA methylation in genes involved in metabolism. Show less