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Danish Iqbal, Mohammed Alsaweed, Qazi Mohammad Sajid Jamal +7 more ยท 2023 ยท Biomolecules ยท MDPI ยท added 2026-04-24
Neurodegenerative disorders, such as Alzheimer's disease (AD), negatively affect the economic and psychological system. For AD, there is still a lack of disease-altering treatments and promising cures Show more
Neurodegenerative disorders, such as Alzheimer's disease (AD), negatively affect the economic and psychological system. For AD, there is still a lack of disease-altering treatments and promising cures due to its complex pathophysiology. In this study, we computationally screened the natural database of fungal metabolites against three known therapeutic target proteins of AD. Initially, a pharmacophore-based, drug-likeness category was employed for screening, and it filtered the 14 ( Show less
๐Ÿ“„ PDF DOI: 10.3390/biom13111613
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