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Loss-of-function mutations in ADCY3 cause monogenic severe obesity.

Sadia Saeed, Amélie Bonnefond, Filippo Tamanini +25 more · 2018 · Nature genetics · Nature · added 2026-04-24

Study of monogenic forms of obesity has demonstrated the pivotal role of the central leptin-melanocortin pathway in controlling energy balance, appetite and body weight

no PDF DOI: 10.1038/s41588-017-0023-6

ADCY3

👤 Filippo Tamanini

Loss-of-function mutations in ADCY3 cause monogenic severe obesity.